Tweets of @EricTopol

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@EricTopol
Eric Topol

130 385 Google this image

It seems the people who write the vaccines w/ a booster aren't working against Omicron are completely out of touch with the data
I'd consider ~90% effectiveness vs hospitalization pretty, pretty damn good
https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1046853/technical-briefing-34-14-january-2022.pdf
Especially compared with 44% without a booster https://twitter.com/EricTopol/status/1483543711623512065/photo/1

@EricTopol
Eric Topol

9 77 Google this image

Last point, which I cannot emphasize enough:
3rd shot protection vs Omicron hospitalizations, severe disease, death is remarkably high, about as well preserved as 2 shots vs ancestral strain, and a very different look compared with VE vs infections
https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1046853/technical-briefing-34-14-january-2022.pdf https://twitter.com/EricTopol/status/1483302665899577345/photo/1

@EricTopol
Eric Topol

21 93 Google this image

“The spectrum of illness reminds us of other seasonal presentation of illnesses that we commonly care for — asthma, croup and bronchiolitis. It is almost as though Covid has replaced some of the usual actors”
The risk for subsequent PIMS is yet unknown https://twitter.com/EricTopol/status/1483445039250345986/photo/1

@EricTopol
Eric Topol

9 77 Google this image

Last point, which I cannot emphasize enough:
3rd shot protection vs Omicron hospitalizations, severe disease, death is remarkably high, about as well preserved as 2 shots vs ancestral strain, and a very different look compared with VE vs infections
https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1046853/technical-briefing-34-14-january-2022.pdf https://twitter.com/EricTopol/status/1483302665899577345/photo/1

@EricTopol
Eric Topol

130 385 Google this image

It seems the people who write the vaccines w/ a booster aren't working against Omicron are completely out of touch with the data
I'd consider ~90% effectiveness vs hospitalization pretty, pretty damn good
https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1046853/technical-briefing-34-14-january-2022.pdf
Especially compared with 44% without a booster https://twitter.com/EricTopol/status/1483543711623512065/photo/1

@EricTopol
Eric Topol

13 47 Google this image

It falls off pretty fast, this vs Omicron (and Delta) symptomatic infections. So an important unresolved question is whether the 4th dose helps prevents this attrition of VE over time vs symptomatic infection and severe disease https://twitter.com/EricTopol/status/1483296971838214146/photo/1

@EricTopol
Eric Topol

23 71 Google this image

The new data for booster vaccine effectiveness vs symptomatic infections, Delta and Omicron. At each time point with Omicron, Moderna 3rd shot still looking somewhat better than Pfizer https://twitter.com/EricTopol/status/1482070658859233281/photo/1

@EricTopol
Eric Topol

6 26 Google this image

Last week @UKHSA published their new data on Omicron and 2 dose vs 3 dose vaccine effectiveness (VE) vs infections https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1046853/technical-briefing-34-14-january-2022.pdf
In people w/o prior Covid, the booster approximately doubled VE, the 62% isn't bad (point estimate)
But https://twitter.com/EricTopol/status/1483296966721212416/photo/1

@EricTopol
Eric Topol

9 28 Google this image

There is also added protection vs infection with the booster: VE 62% in people without prior Covid, only 32% with 2 doses
Less of a bump in people with Prior Covid, but increased 60 to 71% (overlapping 95% CI) https://twitter.com/EricTopol/status/1482027331895975941/photo/1

@MIKITO_777
知念実希人 小説家・医師

190 515 Google this image

CDCが発表した米国の新型コロナ感染による入院患者ですが、
未接種者では激増しているのに対し、ワクチンを2回以上接種した方ではほんの僅かな増加にとどまり、現在は減少してきてさえいます。 

ワクチンの圧倒的な有効性を示しています。 https://twitter.com/MIKITO_777/status/1483208869270921216/photo/1

@EricTopol
Eric Topol

19 73 Google this image

T cells are our principal defense vs severe disease from Covid.
This new edge adds to the 6 recent reports of protective T cells with 2-shot vaccination, summarized here https://twitter.com/EricTopol/status/1482842273062678528/photo/1

@EricTopol
Eric Topol

135 442 Google this image

In just a week, 6 new studies have now reported how T cells, induced from multiple vaccines or prior Covid, hold up quite well vs Omicron (i.e. they exhibit cross-reactivity), which should help protect vs severe disease https://twitter.com/EricTopol/status/1478138671257645056/photo/1

@EricTopol
Eric Topol

31 113 Google this image

The mass confusion surrounding boosters and this big, long miss led a substantial proportion of Americans unnecessarily vulnerable to Delta, and now to Omicron
https://www.washingtonpost.com/opinions/2021/11/24/cdc-got-it-wrong-it-should-have-urged-all-adults-get-covid-19-booster-shots/ (written before Omicron reported) https://twitter.com/EricTopol/status/1482811646258991107/photo/1

@EricTopol
Eric Topol

59 138 Google this image

Our editorial on boosters, @mtosterholm @PostOpinions
"Each day in the United States, the number of people with waning immunity greatly exceeds those who are getting newly vaccinated"
https://www.washingtonpost.com/opinions/2021/11/24/cdc-got-it-wrong-it-should-have-urged-all-adults-get-covid-19-booster-shots/ https://twitter.com/EricTopol/status/1465008429051777029/photo/1

@la_neige_haruki
chocolat viennois ☕

118 171 Google this image

4回目接種しているイスラエルでさえ感染者急増しているだから、ワクチン接種証明だけで経済回すのは無理っていいかげん理解して欲しい。 https://twitter.com/la_neige_haruki/status/1483280355377311745/photo/1